He whanaketanga nui a ActiTide™ Bouncera i roto i ngā kai whakapaipai e ahu mai ana i te peptide, e tuku ana i tētahi otinga ārai-pakeke matatau i hangaia hei wikitoria i ngā herenga o mua o te bioavailability o te peptide. Ahakoa e mōhiotia ana ngā peptide mō ō rātou kaha tohu koiora, he maha ngā wā ka herea tō rātou whakamahinga mahi e te hydrophilicity teitei me te rahi ngota nui, e aukati ana i tō rātou kaha ki te uru ki roto i te stratum corneum momona-ngako o te kiri. Ka aro atu a ActiTide™ Bouncera ki ēnei wero mā te whakauru i tētahi matatini peptide-toru mahi tahi me te hangarau tuku hou.
Te wikitoria i ngā arai tuku me te hangarau Supramolecular
He maha ngā wā ka pāngia ngā peptide tuku iho e te ngoikore o te mimiti transdermal, ka mutu ka noho tonu ngā matū hohe ki te mata o te kiri me te kore e tae atu ki ngā paparanga kiri e hiahiatia ana. Ka whakatauhia tēnei e ActiTide™ Bouncera mā te whakamahi i te Hangarau Penetration Synergistic Supramolecular, e whakaatu ana i ngā wai ionic supramolecular DES-TG.
Mā tēnei huarahi auaha ka hangaia he pūnaha tuku kua tauritehia, ka whakaritea ngā peptides—Palmitoyl Tripeptide-5, Hexapeptide-9, me Hexapeptide-11—ki roto i tētahi matatini supramolecular. Ka whakatikatikahia e tēnei hangarau te urunga o te ārai kiri i roto i tētahi tikanga whakahaere, "hoa ki te hanganga", kia pai ai te pana o ngā matū hohe ki roto i te kiri hohonu me te kiri o roto, me te kore e whakararu i te āhua tūturu o te kiri.
Te Whakaurunga me te Wātea Koiora kua Whakamanahia
Ko te hiranga hangarau o ActiTide™ Bouncera e whakaūtia ana e ngā rangahau werohanga kiri in vitro pakari. Mā te whakamahi i te hangarau whaihanga fluorescence matatau, i aromatawaihia ngā āhuatanga werohanga o ngā peptide takitahi i roto i te matatini. I whakaatuhia e te rangahau ka eke te ActiTide™ Bouncera ki te kaha werohanga e 3 ki te 5 ngā wā i tērā o te rōpū whakahaere mō ia peptide takitahi. I whakaūhia e te whakaahua fluorescence te arotahi hohonu ki te kiri, me te whakarite kia tae atu ngā matū hohe o te biopeptide ki ngā fibroblasts me te Dermal-Epidermal Junction (DEJ) ki reira ka taea e rātou te whakaatu i te pānga tino nui.
Te Whai Huatanga Maha-Whāinga me te Hanga Anō i te Kiri
Haunga tōna tuku pai rawa atu, ka whakaatuhia e ActiTide™ Bouncera te kaha koiora hohonu puta noa i ngā ara koroheketanga maha i roto i ngā rangahau whakamātautau:
Tautoko Hanganga DEJ: Ka whakanui ake i te whakaaturanga ira o te Collagen IV me te VII, arā, ngā pūmua nui hei whakapakari i te Hononga Kiri-Epidermal me te whakaora i te tautoko taketake o te kiri.
Te Hanganga Koratene: I roto i ngā whakamātautau whai huatanga, ko te kukū o te 0.15% anake i whakatairanga i te hanganga Koratene Momo I mā te 332.32%, e whakaatu ana i te kaha ki te whakamātotoru i te kiri me te whakaiti i te hohonutanga o ngā kita.
Te aukati i te pakaru o te collagen me te ngaronga o te collagen: Ka whakarato i tētahi parepare kaha mā te aukati i te MMP-1 (te whākōkī e kawenga ana mō te pakaru o te collagen). I te kukū 0.10%, i heke ngā taumata MMP-1 mā te 94.66%, he pai ake i te Huaora C i roto i te whai huatanga whakatairite.
Ngā Āhuatanga Matatini me ngā Whakamahinga
I runga i te āhua ā-tinana, he wai mārama, mārama rānei te ActiTide™ Bouncera, he mea hanga kia tino pumau, kia ngāwari hoki te hanga. He tino hototahi ki te whānuitanga o ngā hua tiaki kiri kounga teitei, tae atu ki ngā serum kounga teitei, ngā kirīmi whakakaha, me ngā kopare whakaora. Ko te horopeta kua tūtohutia o te 0.2–5.0% ka taea te whakamahi whānui i roto i ngā hanganga e aro ana ki te whakaiti i ngā kita hohonu me te whakaora hanganga o te kiri.
Hei whakarāpopototanga, ko te ActiTide™ Bouncera te whakaaturanga o tētahi peke hangarau mai i te whakamahinga peptide tuku iho ki te tuku hangarau koiora matatau. Mā te whakakotahi i te tika o tētahi matatini peptide-toru me te mana o te Supramolecular Synergistic Penetration, ka whakaratohia he otinga parakore teitei me te mahi teitei mō te whakatupuranga hou o ngā mahi tiaki kiri ngaio. Ko tōna haumaru kua whakaatuhia, te kaha ki te whakauru hohonu (e 3-5 ngā wā te urunga atu i ngā mana whakahaere paerewa), me tōna whai huatanga whakamiharo e whakanoho ana i a ia hei wāhanga rautaki mō ngā waitohu whakapaipai o te ao e rapu ana i ngā hua kua whakamanahia e te pūtaiao.
Wā tuku: Hanuere-07-2026