| Ingoa waitohu | ActiTide-AH3 |
| CAS No. | 616204-22-9 |
| INCI Ingoa | Acetyl Hexapeptide-8 |
| Taupānga | Lotion, Serums, Mask, Horoi kanohi |
| Mōkī | 100g/pounamu, 1kg/pueke |
| Te ahua | Ma ki te paura ma |
| Wairewa | Wairewa wai |
| Mahi | Te raupapa peptide |
| Te ora papa | 2 tau |
| Rokiroki | Whakaorangia te ipu kua kati katia ki te waahi makariri, maroke i te 2 - 8°C. |
| Inenga | 0.005-0.05% |
Taupānga
Ko te rangahau ki nga tikanga whakakorikori taketake i kitea ai te ActiTide-AH3, he hexapeptide auaha i whakawhanakehia ma te huarahi putaiao mai i te hoahoa whaitake ki te hanga GMP, me nga hua pai.
Ka tukuna e ActiTide-AH3 te kaha whakaheke korukoru e rite ana ki te Botulinum Toxin Momo A, me te karo i nga tupono werohanga me te utu nui ake.
Painga Paku:
Ko te ActiTide-AH3 he whakaiti i te hohonu o te korukoru na te whakahekenga o nga uaua kanohi, me nga paanga ki runga i te rae me nga kita korikori.
Hangahanga Mahi:
Ko te whakahekenga o te uaua ka puta i te tukunga o te neurotransmitter mai i nga vesicles synaptic. Ko te matatini SNARE - he huihuinga ternary o VAMP, Syntaxin, me te SNAP-25 pūmua - he mea nui mo te vesicles docking me te neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Ko tenei matatini ka mahi hei matau pukoro, hei hopu i nga vesicles me te taraiwa i te whakakotahitanga membrane.
Hei tauira hangahanga o te SNAP-25 N-terminus, ka whakataetae a ActiTide-AH3 me SNAP-25 mo te whakauru ki roto i te matatini SNARE, me te whakarereke i tana huihuinga. Ko te whakararu o te matatini SNARE ka whakararu i te tauranga vesicles me te tukunga o te neurotransmitter o muri mai, ka heke te whakaheke o nga uaua me te aukati i te korukoru me te hanga raina pai.
Ko te ActiTide-AH3 he mea haumaru ake, he ohaoha, he ngawari ake ki te Botulinum Toxin Momo A. Ko te huarahi e whai ana i runga ake i te ara hanga korukoru kotahi engari ka mahi ma te tikanga motuhake.
